Journal: Cancer Science

Article Title: Frequency of unsatisfactory cervical cytology smears in cancer screening of Japanese women: A systematic review and meta‐analysis

doi: 10.1111/cas.13549

Figure Lengend Snippet: Meta‐analysis of the unsatisfactory specimen rate using liquid‐based cytology in the primary cervical cancer screening setting in Japan, according to cytology platform and sampling device. Diamonds depict the summary unsatisfactory rate with the 95% confidence interval ( CI ). Each square and horizontal line indicates the unsatisfactory rate and the corresponding 95% CI , respectively, for each study. Collection devices: CervexBrush (Rovers Medical Devices, Oss, Netherlands); SurePath (Becton Dickinson, Franklin Lakes, NJ , USA ); TACAS Pro (Medical & Biological Laboratories, Nagoya, Japan); and ThinPrep (Hologic Inc., Marlborough, MA , USA ). Misc, data based on joint analysis of multiple different collection devices

Article Snippet: We calculated the I 2 statistics with their 95% CIs, and considered I 2 of >50% or >75% to be suggestive of intermediate or high heterogeneity, respectively., Subgroup analyses and univariate meta‐regression were carried out for sample collection devices (cotton swab vs other non‐cotton swab collection devices combined) and commercial platforms for LBC (SurePath [Becton Dickinson, Franklin Lakes, NJ, USA] vs all other platforms).

Techniques: Sampling

Journal: Cancer Science

Article Title: Frequency of unsatisfactory cervical cytology smears in cancer screening of Japanese women: A systematic review and meta‐analysis

doi: 10.1111/cas.13549

Figure Lengend Snippet: Meta‐analysis of studies that compared unsatisfactory specimen rates between conventional cytology ( CC ) and liquid‐based cytology ( LBC ) in the primary cervical cancer screening setting in Japan. Diamonds depict the summary odds ratio with the 95% confidence interval ( CI ). Each square and horizontal line indicates the odds ratio and the corresponding 95% CI , respectively, for each study. Point estimates and their 95% CI s are based on the “empirical” continuity zero‐event correction

Article Snippet: We calculated the I 2 statistics with their 95% CIs, and considered I 2 of >50% or >75% to be suggestive of intermediate or high heterogeneity, respectively., Subgroup analyses and univariate meta‐regression were carried out for sample collection devices (cotton swab vs other non‐cotton swab collection devices combined) and commercial platforms for LBC (SurePath [Becton Dickinson, Franklin Lakes, NJ, USA] vs all other platforms).

Techniques:

Journal: British Journal of Cancer

Article Title: Cervical histology after routine ThinPrep or SurePath liquid-based cytology and computer-assisted reading in Denmark

doi: 10.1038/bjc.2015.339

Figure Lengend Snippet: Description of phases by laboratory

Article Snippet: Change in the technology , FocalPoint Slide Profiler 50% cutoff , SurePath LBC , FocalPoint Slide Profiler cutoff decreased to 25%, HC2 triage of ASCUS , FocalPoint GS Imaging System.

Techniques: Imaging

Journal: British Journal of Cancer

Article Title: Cervical histology after routine ThinPrep or SurePath liquid-based cytology and computer-assisted reading in Denmark

doi: 10.1038/bjc.2015.339

Figure Lengend Snippet: Primary cytology samples and histological outcomes after 2.5-year follow-up a

Article Snippet: Change in the technology , FocalPoint Slide Profiler 50% cutoff , SurePath LBC , FocalPoint Slide Profiler cutoff decreased to 25%, HC2 triage of ASCUS , FocalPoint GS Imaging System.

Techniques: Imaging

Journal: British Journal of Cancer

Article Title: Cervical histology after routine ThinPrep or SurePath liquid-based cytology and computer-assisted reading in Denmark

doi: 10.1038/bjc.2015.339

Figure Lengend Snippet: Effect of full implementation of SurePath/FocalPoint or ThinPrep LBC and computer-assisted reading (last phase) a

Article Snippet: Change in the technology , FocalPoint Slide Profiler 50% cutoff , SurePath LBC , FocalPoint Slide Profiler cutoff decreased to 25%, HC2 triage of ASCUS , FocalPoint GS Imaging System.

Techniques: Imaging

Journal: British Journal of Cancer

Article Title: Cervical histology after routine ThinPrep or SurePath liquid-based cytology and computer-assisted reading in Denmark

doi: 10.1038/bjc.2015.339

Figure Lengend Snippet: Frequency of histologically confirmed ⩾CIN2, by laboratory and phase. Roskilde: manually read conventional cytology in all phases. Hvidovre and Hillerød: SurePath/FocalPoint reading and liquid-based cytology technologies. Odense: ThinPrep reading and liquid-based cytology technologies. ○, 23–29 years; □, 30–44 years; ◊, 45–59 years. Phases as described in . CPH M, Copenhagen Municipality.

Article Snippet: Change in the technology , FocalPoint Slide Profiler 50% cutoff , SurePath LBC , FocalPoint Slide Profiler cutoff decreased to 25%, HC2 triage of ASCUS , FocalPoint GS Imaging System.

Techniques:

Journal: British Journal of Cancer

Article Title: Cervical histology after routine ThinPrep or SurePath liquid-based cytology and computer-assisted reading in Denmark

doi: 10.1038/bjc.2015.339

Figure Lengend Snippet: Frequency of histologically confirmed

Article Snippet: Change in the technology , FocalPoint Slide Profiler 50% cutoff , SurePath LBC , FocalPoint Slide Profiler cutoff decreased to 25%, HC2 triage of ASCUS , FocalPoint GS Imaging System.

Techniques:

Journal: British Journal of Cancer

Article Title: Cervical histology after routine ThinPrep or SurePath liquid-based cytology and computer-assisted reading in Denmark

doi: 10.1038/bjc.2015.339

Figure Lengend Snippet: Frequency of false-positive tests for ⩾CIN2 (samples with abnormal cytology that were not followed by a histological diagnosis of ⩾CIN2), by laboratory and phase. Roskilde: manually read conventional cytology in all phases. Hvidovre and Hillerød: SurePath/FocalPoint reading and liquid-based cytology technologies. Odense: ThinPrep reading and liquid-based cytology technologies. ○, 23–29 years; □, 30–44 years; ◊, 45–59 years. Phases as described in . CPH M, Copenhagen Municipality.

Article Snippet: Change in the technology , FocalPoint Slide Profiler 50% cutoff , SurePath LBC , FocalPoint Slide Profiler cutoff decreased to 25%, HC2 triage of ASCUS , FocalPoint GS Imaging System.

Techniques: Biomarker Discovery

Journal: British Journal of Cancer

Article Title: Cervical histology after routine ThinPrep or SurePath liquid-based cytology and computer-assisted reading in Denmark

doi: 10.1038/bjc.2015.339

Figure Lengend Snippet: Laboratory with SurePath cytological technology (Hvidovre/Copenhagen Municipality) a

Article Snippet: Change in the technology , FocalPoint Slide Profiler 50% cutoff , SurePath LBC , FocalPoint Slide Profiler cutoff decreased to 25%, HC2 triage of ASCUS , FocalPoint GS Imaging System.

Techniques: Imaging

Journal: British Journal of Cancer

Article Title: Cervical histology after routine ThinPrep or SurePath liquid-based cytology and computer-assisted reading in Denmark

doi: 10.1038/bjc.2015.339

Figure Lengend Snippet: Laboratory with SurePath cytological technology (Hvidovre/Frederiksberg Municipality) a

Article Snippet: Change in the technology , FocalPoint Slide Profiler 50% cutoff , SurePath LBC , FocalPoint Slide Profiler cutoff decreased to 25%, HC2 triage of ASCUS , FocalPoint GS Imaging System.

Techniques: Imaging

Journal: British Journal of Cancer

Article Title: Cervical histology after routine ThinPrep or SurePath liquid-based cytology and computer-assisted reading in Denmark

doi: 10.1038/bjc.2015.339

Figure Lengend Snippet: Laboratory with SurePath cytological technology (Hillerød) a

Article Snippet: Change in the technology , FocalPoint Slide Profiler 50% cutoff , SurePath LBC , FocalPoint Slide Profiler cutoff decreased to 25%, HC2 triage of ASCUS , FocalPoint GS Imaging System.

Techniques: Imaging

Journal: British Journal of Cancer

Article Title: Cervical histology after routine ThinPrep or SurePath liquid-based cytology and computer-assisted reading in Denmark

doi: 10.1038/bjc.2015.339

Figure Lengend Snippet: Effect of full implementation of SurePath/FocalPoint or ThinPrep LBC and computer-assisted reading (last phase) a

Article Snippet: In Hvidovre/Copenhagen, full implementation of SurePath/FocalPoint LBC and reading technologies compared with manually read conventional cytology was associated with a doubling of the frequency of all studied outcomes at 23–44 years, with the exception of a decreased PPV for ⩾CIN2/⩾CIN3.

Techniques: Imaging

Journal: British Journal of Cancer

Article Title: Cervical histology after routine ThinPrep or SurePath liquid-based cytology and computer-assisted reading in Denmark

doi: 10.1038/bjc.2015.339

Figure Lengend Snippet: Frequency of histologically confirmed ⩾CIN2, by laboratory and phase. Roskilde: manually read conventional cytology in all phases. Hvidovre and Hillerød: SurePath/FocalPoint reading and liquid-based cytology technologies. Odense: ThinPrep reading and liquid-based cytology technologies. ○, 23–29 years; □, 30–44 years; ◊, 45–59 years. Phases as described in . CPH M, Copenhagen Municipality.

Article Snippet: In Hvidovre/Copenhagen, full implementation of SurePath/FocalPoint LBC and reading technologies compared with manually read conventional cytology was associated with a doubling of the frequency of all studied outcomes at 23–44 years, with the exception of a decreased PPV for ⩾CIN2/⩾CIN3.

Techniques:

Journal: British Journal of Cancer

Article Title: Cervical histology after routine ThinPrep or SurePath liquid-based cytology and computer-assisted reading in Denmark

doi: 10.1038/bjc.2015.339

Figure Lengend Snippet: Frequency of histologically confirmed

Article Snippet: In Hvidovre/Copenhagen, full implementation of SurePath/FocalPoint LBC and reading technologies compared with manually read conventional cytology was associated with a doubling of the frequency of all studied outcomes at 23–44 years, with the exception of a decreased PPV for ⩾CIN2/⩾CIN3.

Techniques:

Journal: British Journal of Cancer

Article Title: Cervical histology after routine ThinPrep or SurePath liquid-based cytology and computer-assisted reading in Denmark

doi: 10.1038/bjc.2015.339

Figure Lengend Snippet: Frequency of false-positive tests for ⩾CIN2 (samples with abnormal cytology that were not followed by a histological diagnosis of ⩾CIN2), by laboratory and phase. Roskilde: manually read conventional cytology in all phases. Hvidovre and Hillerød: SurePath/FocalPoint reading and liquid-based cytology technologies. Odense: ThinPrep reading and liquid-based cytology technologies. ○, 23–29 years; □, 30–44 years; ◊, 45–59 years. Phases as described in . CPH M, Copenhagen Municipality.

Article Snippet: In Hvidovre/Copenhagen, full implementation of SurePath/FocalPoint LBC and reading technologies compared with manually read conventional cytology was associated with a doubling of the frequency of all studied outcomes at 23–44 years, with the exception of a decreased PPV for ⩾CIN2/⩾CIN3.

Techniques: Biomarker Discovery